包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
Lenalidomide-propargyl-C2-amido-Ph-NH2 HCl incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase and a linker. Lenalidomide-propargyl-C2-amido-Ph-NH2 HCl can be used to design the PROTAC MD-224 (HY-114312). References: [1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis TargetingChimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable TumorRegression. J Med Chem. 2019 Jan 24;62(2):448-466.
纯度:≥98%