AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12F36V-directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules[1].

dTAG molecules engage FKBP12F36V and CRBN[1].

2230613-03-1

C38H47NO11

693.78

PROTAC FKBP12-binding moiety 2

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years