Isoforskolin 源自毛喉鞘蕊花,可减少人单核白细胞中 TNF-α、IL-1β、IL-6 和 IL-8 的分泌。Isoforskolin 可用于治疗莱姆关节炎的研究。
产品描述
Isoforskolin is derived from Coleus forskohlii and reduces the secretion of TNF-α, IL-1β, IL-6 and IL-8 in human mononuclear leukocytes. Isoforskolin can be used in studies about the treatment of Lyme arthritis.
体内活性
Isoforskolin downregulats the transcription and expression of TNF-α and IL-6 induced by rBmpA in mice. Isoforskolin inhibits the symptoms of experimental Lyme arthritis[1].
Cas No.
64657-21-2
分子式
C22H34O7
分子量
410.5
储存和溶解度
DMSO:2.1 mg/mL (5 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years