(Rac)-LM11A-31 dihydrochloride

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CAS NO:

1214672-15-7

包装与价格：

产品介绍

(Rac)-LM11A-31 dihydrochloride 是 LM11A-31 dihydrochloride 的异构体。LM11A-31 dihydrochloride 是一种 p75NTR (神经营养蛋白受体 p75) 配体，是有效的 proNGF 拮抗剂。

Cas No.	1214672-15-7
别名	2-氨基-3-甲基-N-[2-(吗啉-4-基)乙基]戊酰胺二盐酸
Canonical SMILES	CCC(C)C(N)C(NCCN1CCOCC1)=O.[H]Cl.[H]Cl
分子式	C₁₂H₂₇Cl₂N₃O₂
分子量	316.27
溶解度	Water: ≥ 200 mg/mL (632.37 mM); Ethanol: 100 mg/mL (316.19 mM)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist[1]. [1]. Elshaer SL, et al. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinalvascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway. Diabetologia. 2019 Aug;62(8):1488-1500.