NPC 567 acetate 是一种缓激肽 B2 拮抗剂,可用于治疗过敏性气道疾病的研究。
产品描述
NPC 567 acetate is a bradykinin B2 antagonist and can be used in studies about the treatment of allergic airway disease.
体内活性
In the NPC 567 acetate (2.5 mg) -treated pigs, the resistance only increased from 2.9 cm H2O/l/s to 6.5 cm H2O/l/s. There was also a higher reduction in dynamic lung compliance in the controls than in the treated animals upon allergen challenge. The histamine concentration in urine in the control pigs was markedly elevated after allergen challenge peaking at 15-30 min. This release was inhibited in the NPC 567 acetate-treated pigs[1].
Cas No.
T21060L
分子式
C62H91N19O15
分子量
1342.5
别名
NPC 567 acetate(109333-26-8 Free base)
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years