ICATibant acetate 是一种特异性缓激肽 B2 受体拮抗剂，其IC50=1.07 nM，Ki=0.798 nM。

Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema.

Icatibant is a decapeptide resistant to the bradykinin-degrading proteases, leading to a longer half-life than bradykinin which it antagonizes[1].

Icatibant treatment exhibits efficacy in bradykinin-mediated angioedema attacks, and rapidly relieves symptom [1].

138614-30-9

C61H93N19O15S

1364.57

DMSO:100 mg/mL (73.28 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years