Nitroprusside disodium dehydrate 是一种血管扩张剂，通过在血液中自发释放 NO 发挥作用。它可在谷胱甘肽耗竭的成骨细胞中诱导自噬，用于急性高血压和心力衰竭的研究。

Sodium Nitroprusside Dihydrate is a potent vasodilator working through releasing NO spontaneously in blood.

Sodium Nitroprusside is a potent vasodilator. Sodium nitroprusside has potent vasodilating effects in arterioles and venules. Sodium Nitroprusside breaks down in circulation to release nitric oxide (NO). NO activates guanylate cyclase in vascular smooth muscle and increases intracellular production of cGMP. The end result is vascular smooth muscle relaxation, which allow vessels to dilate. [1] Sodium nitroprusside decreases the proliferation of vascular smooth muscle cells. [2]

Sodium nitroprusside (5 mg/kg) significantly reduces the intestinal ischemiareperfusion injury as a nitric oxide donor in rats. [3]

13755-38-9

C5H4FeN6Na2O3

297.951

硝普钠二水合物;硝普钠;Sodium Nitroprusside Dihydrate;Sodium Nitroferricyanide(III) Dihydrate

DMSO:56 mg/mL (188 mM)
Ethanol:<1 mgml
H2O:55 mg/mL (184.6 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years