NIBR189是 EBI2（GPR183）小分子拮抗剂(IC50:11 nM)。

NIBR189 is a potent and selective antagonist of EBI2 (GPR183) receptor (IC50 of 11 and 15 nM for human and mouse EBI2 receptors, respectively)

NIBR189 is selective for EBI2 over a panel of other receptors, enzymes, and transporters.?NIBR189 blocks the oxysterol-induced migration of U937 monocytic cells.

1599432-08-2

C21H21BrN2O3

429.32

DMSO:47 mg/mL (109.48 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years