Glycerol phenylbutyrate 是一种氨清除剂,也是 sigma-2 受体配体,pKi为8.02。
产品描述
Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
体内活性
Glycerol phenylbutyrate may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders. Glycerol phenylbutyrate also has the potential for the treatment of hyperammonemia. [1][2].
Cas No.
611168-24-2
分子式
C33H38O6
分子量
530.65
别名
苯丁酸甘油酯;HPN-100
储存和溶解度
DMSO:150 mg/mL (282.67 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years