| CAS NO: | 462100-06-7 |
| 包装: | 100mg |
| 市场价: | 900元 |
| Cas No. | 462100-06-7 |
| 别名 | 5,8,11-三氧杂-2-氮杂十三烷二酸1-叔丁酯 |
| Canonical SMILES | O=C(OC(C)(C)C)NCCOCCOCCOCC(O)=O |
| 分子式 | C13H25NO7 |
| 分子量 | 307.34 |
| 溶解度 | DMF: 5 mg/ml,DMSO: 1 mg/ml,Ethanol: 30 mg/ml |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. [1]. Vollmer S, et al. Design, Synthesis, and Biological Evaluation of MEK PROTACs. J Med Chem. 2020 Jan 9;63(1):157-162. |
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