(-)-Denudatin B 源自 Magnolia fargesii。 (-)-Denudatin B 通过抑制胶原蛋白和凝血酶诱导的磷酸肌醇分解，在高浓度下具有非特异性抗血小板作用。

(-)-Denudatin B is derived from Magnolia fargesii. (-)-Denudatin B has nonspecific antiplatelet action at high concentration by inhibiting phosphoinositides breakdown induced by collagen and thrombin.

Denudatin B inhibits the aggregation and ATP release of washed rabbit platelets caused by platelet-activating factor (PAF) in a concentration-dependent manner. High concentration of Denudatin B (greater than 50 micrograms/ml) inhibits the aggregation and ATP release of platelets caused by ADP, collagen, arachidonic acid and thrombin. Denudatin B suppresses thrombin-induced rise of the intracellular calcium concentration[1].

87402-88-8

C21H24O5

356.41

Denudatin B

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years