Avexitide 是一种特异竞争性的glucagon-like peptide-1 (GLP-1)受体拮抗剂。
产品描述
Avexitide (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor.
体外活性
Avexitide (Exendin (9-39)) is a specific GLP-1 receptor antagonist which is a truncated form of the GLP-1 agonist exendin-4. GLP-1 plays a role in the control of fasting glucose.
体内活性
Continuous subcutaneous infusion of Avexitide (Exendin (9-39)) significantly raises fasting blood glucose levels in SUR-1 mice without affecting glucose tolerance-/-.
Cas No.
133514-43-9
分子式
C149H234N40O47S
分子量
3369.8
别名
Exendin (9-39);艾塞那肽;Exendin-3 (9-39) amide
储存和溶解度
H2O:49 mg/mL (14.54 mM),Need ultrasonic
H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years