| CAS NO: | 10297-09-3 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 500mg | 电议 |
| Cas No. | 10297-09-3 |
| 别名 | 7-辛酸 |
| Canonical SMILES | C#CCCCCCC(O)=O |
| 分子式 | C8H12O2 |
| 分子量 | 140.18 |
| 溶解度 | DMSO: 150 mg/mL (1070.05 mM); Water: 5 mg/mL (35.67 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 7-Octynoic acid (compound 42) is a PROTAC linker and can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17. |
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