| CAS NO: | 117235-10-6 |
| 包装: | 500mg |
| 市场价: | 540元 |
| Cas No. | 117235-10-6 |
| 别名 | 3-巯基丙烷基-N-羟基琥珀酰亚胺酯 |
| Canonical SMILES | O=C(ON1C(CCC1=O)=O)CCS |
| 分子式 | C7H9NO4S |
| 分子量 | 203.22 |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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