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Phellopterin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Phellopterin图片
CAS NO:2543-94-4
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Phellopterin 是从 P. trifoliata 中分离得到的天然产物。Phellopterin 通过调节 Akt 和 PKC 通路降低 TNF-alpha 诱导的 VCAM-1 表达,从而抑制单核细胞与内皮细胞的粘附。
Cas No.2543-94-4
别名珊瑚菜素
Canonical SMILESO=C1C=CC2=C(OC)C3=C(OC=C3)C(OC/C=C(C)/C)=C2O1
分子式C17H16O5
分子量300.31
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Phellopterin is a natural product isolated from P. trifoliata. Phellopterin reduce TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1].

[1]. Nizamutdinova IT, et al. Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells. Int Immunopharmacol. 2008 May;8(5):670-8.