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cis-VZ 185
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
cis-VZ 185图片
CAS NO:2306193-98-4
包装:5mg
市场价:3660元

产品介绍
Cas No.2306193-98-4
Canonical SMILESCOC1=CC(C2=CN(C(C3=CN=CC=C23)=O)C)=CC(OC)=C1CN4CCN(CC4)CCCCCOC5=C(C=CC(C6=C(N=CS6)C)=C5)CNC([C@@H]7C[C@@H](CN7C([C@H](C(C)(C)C)NC(C8(CC8)F)=O)=O)O)=O
分子式C53H67FN8O8S
分子量995.23
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Negative control for VZ 185 .

Zoppi et al (2019) Iterative design and optimization of initially inactive proteolysis targeting chimeras (PROTACs) identify VZ185 as a potent, fast, and selective Von Hippel-Lindau (VHL) based dual degrader probe of BRD9 and BRD7. J.Med.Chem. 62 699 PMID:30540463