LY2812223 is a highly effective and functionally selective mGlu2 receptor agonist. It has a mGlu2 binding affinity for mGlu2 and mGlu3 (Ki=144 nM and 156 nM, respectively).

1311385-20-2

C10H12N4O4S

284.29

H2O:50 mg/mL (175.88 mM),Need ultrasonic
DMSO:28.75 mg/mL (101.13 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years