Y16 是一种 G 蛋白偶联的 Rho GEFs 抑制剂，与 Rhosin/G04 协同作用，抑制 LARG-RhoA 相互作用、RhoA 激活和 RhoA 介导的信号传导功能。它是LARG的特异性抑制剂，Kd值为 76 nM。

Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions.

429653-73-6

C24H20N2O3

384.435

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years