YH-306 是 FAK 信号通路的调节剂。 YH-306 显示出抗肿瘤活性，抑制结直肠肿瘤的生长和转移。

YH-306 is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.

YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1, and the expression of MMP2 and MMP9. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 inhibits Arp2/3 complex-mediated actin polymerization[1].

1373764-75-0

C19H18N2O2

306.36

DMSO:15 mg/mL?(48.96 mM),ultrasonic and adjust pH to 1 with HCl
Powder: -20°C for 3 years
In solvent: -80°C for 2 years