MLS000532223 是一种具有高亲和力的 Rho 家族 GTPases 选择性抑制剂，其EC50=16~120 μM。它能阻止几种 GTPases 同 GTP 的结合。

MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).

MLS000532223, a general inhibitor that prevents GTP binding to several GTPases in a dose-dependent manner and is active in biochemical and cell-based secondary assays.?Live-cell imaging and confocal microscopy studies revealed the inhibitor-induced actin reorganization and cell morphology changes, characteristic of Rho GTPases inhibition.

16616-39-0

C15H9NO3

251.241

DMSO:45mg/ml (179.11 Mm),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years