CCG-222740 是一种口服有效的选择性Rho/MRTF途径抑制剂。它也是 α-平滑肌的肌动蛋白表达抑制剂，可减少皮肤纤维化并阻止黑色素瘤转移。
产品描述
CCG-222740 is an inhibitor of Rho/MRTF pathway
体外活性
CCG-222740 decreases the activation of stellate cells in vitro and in vivo, by reducing the levels of alpha smooth muscle actin(α-SMA) expression[1].
Cas No.
1922098-69-8
分子式
C23H19ClF2N2O3
分子量
444.86
储存和溶解度
DMSO:125 mg/mL (280.99 Mm)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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