MP7 是磷酸肌醇依赖性激酶-1 (PDK1) 抑制剂。

MP7 is a inhibitor of phosphoinositide-dependent kinase-1 (PDK1).

MP7 are able to decrease the number of viable cells. When combined together, GSC viability is further reduced with respect to single-treated cells. As observed in U87MG cells, when used at the highest concentrations (i.e., 1.5 μM Alisertib and 2.5 μM MP7), a significant enhancement in the number of dead cells is evidenced. Following 72 h treatment.

1001409-50-2

C28H22F2N4O4

516.5

PDK1 抑制剂;PDK1 inhibitor

H2O:< 0.1 mg/mL (insoluble)
DMSO:≥ 100 mg/mL (193.61 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years