EzatioSTAT是一种具有造血刺激活性的谷胱甘肽 S-转移酶 (GST) P1-1 的脂质体小分子谷胱甘肽类似物抑制剂。

Ezatiostat is a liposomal small-molecule glutathione analog inhibitor of glutathione S-transferase (GST) P1-1 with hematopoiesis-stimulating activity.

Ezatiostat is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity (Ki = 400 nM) with minimal effect on the related GSTα and -μ families (Kis range from 20-75 μM)[1].

T5862

C29H36F3N3O8S

529.65

Ezatiostat;Ezatiostat TFA (free base);TLK199;TER199(free base)

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years