Quinine 是一种从金鸡纳树皮中提取的生物碱,用于预防和治疗疟疾。它也用于特发性肌肉痉挛,可抑制电压脉冲引起的 MT mSlo3 (KCa5.1) 通道 +100 mV 电流, 其IC50值为 169 μM,是一种钾离子通道抑制剂。
产品描述
Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy has been associated with rare instances of hypersensitivity reactions which can be accompanied by hepatitis and mild jaundice.
Cas No.
130-95-0
分子式
C20H24N2O2
分子量
324.424
别名
奎宁;奎宁树
储存和溶解度
DMSO:10 mM
H2O:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years