Chromeceptin 是 IGF 信号通路的抑制剂,可减少肿瘤球的数量,并抑制 Akt/mTOR 通路。
产品描述
Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.
体外活性
In Hep3B-derived TS cells, Chromeceptin (5 μM) inhibits IGF2 expression in a time-dependent manner. Chromeceptin suppresses IGF-2 expression at mRNA and protein levels in HCC cells[1].
Cas No.
331859-86-0
分子式
C19H16F3N3O
分子量
359.35
储存和溶解度
DMSO:90 mg/mL (250.45 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years