| CAS NO: | 2245697-88-3 |
| 包装: | 25mg |
| 市场价: | 1999元 |
| Cas No. | 2245697-88-3 |
| Canonical SMILES | NCCCCCCOC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O.Cl |
| 分子式 | C19H23N3O5.HCl |
| 分子量 | 409.86 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a C6 alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTACs R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 4 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license. Nabet et al (2018) The dTAG system for immediate and target-specific protein degradation. Nat.Chem.Biol. 14 431 PMID:29581585 |Erb et al (2017) Transcription control by the ENL YEATS domain in acute leukaemia. Nature. 543 270 PMID:28241139 |
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