您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > CSF1R-IN-1
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
CSF1R-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CSF1R-IN-1图片
CAS NO:2095849-04-8
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
CSF1R-IN-1 是一种 CSF1R 抑制剂 (IC50:0.5 nM)。

产品描述

CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.

体外活性

It is believed that CSF1R plays an important role in the recruitment and differentiation of tumor-associated macrophages (TAM). CSF1R-IN-1 showed good intestinal permeability in Caco2 analysis.

体内活性

CSF1R-IN-1 has good pharmacokinetics when administered orally to mice. It seems suitable for in vivo pharmacological testing in an appropriate preclinical tumor model to prove a proof of concept.

Cas No.

2095849-04-8

分子式

C25H20F3N5O2

分子量

479.45

储存和溶解度

DMSO:83.33 mg/mL (173.80 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years