RU-302 是一种 TAM 受体泛抑制剂，可阻断 TAM Ig1 胞外域和 Gas6 Lg 域之间的界面。 RU-302 有效阻断 Gas6 诱导的 AXL 的激活并抑制肺癌肿瘤的生长。

RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks the activation of Gas6-inducible AXL and suppresses lung cancer tumor growth.

1182129-77-6

C24H24F3N3O2S

475.53

DMSO:90 mg/mL (189.26 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years