UNC2541 是 Mer 酪氨酸激酶特异性抑制剂，与 MerTK ATP 结合口袋结合的IC50值为 4.4 nM，对其选择性远高于 Axl，Tyro3 和 FLT3。它能够抑制磷酸化的 MerTK (pMerTK；EC50，510 nM)。

UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).

1612782-86-1

C24H34FN7O2

471.57

DMSO:10 mg/mL (21.21 mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years