KGP94 是一种有效的、选择性的和竞争性的溶酶体内肽酶抑制剂。

KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.

The novel cathepsin L/K inhibitors KGP94 could inhibit in vitro M2 macrophage invasion and reduce the macrophage-stimulated invasion of 4T1 murine breast cancer cells. KGP94 treatment also reduced the expression of several M2-associated markers, suggesting that cathepsin L activity may be important for IL-4-driven M0 to M2 differentiation[1].

1131456-28-4

C14H12BrN3OS

350.23

KGP-94;KGP 94

DMSO:60 mg/ml (171.32 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years