6-Diazo-5-oxo-L-nor-Leucine?是一种谷氨酰胺拮抗剂,具有抗菌、抗病毒和抗癌作用,其Ki值为 6 μM。它能降低肿瘤细胞的自我更新能力和转移能力 ,在体外表现出遗传毒性。
产品描述
L-6-Diazo-5-oxonorleucine is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.
Cas No.
157-03-9
分子式
C6H9N3O3
分子量
171.156
别名
L-6-Diazo-5-oxonorleucine;Diazooxonorleucine;DON;6-重氮-5-氧代-L-正亮氨酸
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years