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Swertiajaponin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Swertiajaponin图片
CAS NO:6980-25-2
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Swertiajaponin 是酪氨酸酶抑制剂,与酪氨酸酶结合囊形成多个氢键和疏水相互作用,IC50=43.47 μM。它能抑制黑色素积累,具有较强的抗氧化活性。它还能通过抑制氧化应激介导的 MAPK/MITF 信号导致酪氨酸酶蛋白水平下降。

产品描述

Swertiajaponin possesses antimicrobial activity.

体外活性

Isolated LDL was incubated with compounds 1-3 and the kinetics of lipid peroxidation were assessed by conjugated diene and malondialdehyde-thiobarbituric acid reactive substances (MDA-TBARS) formation after addition of copper ions. Significant differences (p< 0.05) between the lag time phase of the control and the lag time phase in the presence of the compounds 1 (0.25 microM) and 2 (0.50 microM) were observed. After five hours of incubation all three compounds showed a significant inhibitory effect on MDA-TBARS formation with respect to the control. After six hours of incubation only compound 1 kept a remarkable antioxidant effect[1]

Cas No.

6980-25-2

分子式

C22H22O11

分子量

462.4

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years