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Fmoc-Ala-Ala-Asn(Trt)-OH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fmoc-Ala-Ala-Asn(Trt)-OH图片
CAS NO:1951424-92-2
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Fmoc-Ala-Ala-Asn(Trt)-OH是一种可降解(cleavable)的ADClinker,可用于合成抗体偶联药物(ADC)。
Cas No.1951424-92-2
Canonical SMILESOC([C@@H](NC([C@@H](NC([C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C)=O)C)=O)CC(NC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)=O)=O
分子式C44H42N4O7
分子量738.83
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.