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Deoxycorticosterone acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Deoxycorticosterone acetate图片
CAS NO:56-47-3
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
DOC acetate
醋酸去氧皮质酮
Cortexone acetate
11-Deoxycorticosterone acetate
醋酸脱氧皮质酮
产品介绍
脱氧皮质酮醋酸酯是肾上腺产生的类固醇激素,具有盐皮质激素活性,并作为醛固酮的前体。

产品描述

Desoxycorticosterone acetate is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid.

激酶实验

Kinase inhibition: The ability of compounds to inhibit ATR, ATM or DNAPK kinase activity istested using a radiometric-phosphate incorporation assay. A stock solution isprepared consisting of the appropriate buffer, kinase, and target peptide. To this isadded the compound of interest, at varying concentrations in DMSO to a final DMSO concentration of 7%. Assays are initiated by addition of an appropriate [γ-33P]ATP solution and incubated at 25 ℃. Assays are stopped, after the desired time course, by addition of phosphoric acid and ATP to a final concentration of 100 mM and 0.66 μM, respectively. Peptides are captured on a phosphocellulose membrane, prepared as per manufacturer's instructions, and washed six times with 200 μL of 100 mM phosphoric acid, prior to the addition of 100 μL of scintillation cocktail and scintillation counting on a 1450 Microbeta Liquid Scintillation Counter. Dose?response data are analyzed using GraphPad Prism software

Cas No.

56-47-3

分子式

C23H32O4

分子量

372.5

别名

DOC acetate;醋酸去氧皮质酮;Cortexone acetate;11-Deoxycorticosterone acetate;醋酸脱氧皮质酮

储存和溶解度

DMSO:9 mg/mL (24.2 mM)
H2O:<1 mgml
Ethanol:6 mg/mL (16.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years