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Fmoc-NH-PEG4-CH2CH2COOH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fmoc-NH-PEG4-CH2CH2COOH图片
CAS NO:557756-85-1
包装:100mg
市场价:450元

产品介绍
Fmoc-NH-PEG4-CH2CH2COOH是一种可降解的ADClinker,用于抗体药物偶联物(ADC)合成。
Cas No.557756-85-1
别名5,8,11,14-四氧杂-2-氮杂十七烷二酸1-(9H-芴-9-基甲基)酯,Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid
Canonical SMILESO=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCC(O)=O
分子式C26H33NO8
分子量487.54
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[1]. Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14.