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Estradiol Benzoate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Estradiol Benzoate图片
CAS NO:50-50-0
包装与价格:
包装价格(元)
500 mg电议
1 g电议
1 mL*10 mM(in DMSO)电议

产品名称
苯甲酸雌二醇
Benzoestrofol
Benzhormovarine
Benovocylin
产品介绍
Estradiol BenzOATe 是一种类固醇性激素,是一种雌二醇的前体药物。它表现出轻微的合成代谢特性,增加血液凝固性。

产品描述

Estradiol Benzoate is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females.

体外活性

Estradiol benzoate is asynthetic ester, specifically the 3-benzoyl ester, of the natural estrogen, estradiol. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position and is often used in combination with a progestin to induce estrus in domestic livestock. This compound binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM. This reflects a 6-10 fold reduction in binding affinity compared to estradiol. [1]

Cas No.

50-50-0

分子式

C25H28O3

分子量

376.496

别名

苯甲酸雌二醇;Benzoestrofol;Benzhormovarine;Benovocylin

储存和溶解度

H2O:<1 mgml
DMSO:70 mg/mL (185.9 mM)
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years