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Propylthiouracil
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Propylthiouracil图片
CAS NO:51-52-5
包装与价格:
包装价格(元)
100 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
6-Propyl-2-thiouracil
丙基硫氧嘧啶
6-n-Propylthiouracil
NSC 6498
Pseudocapsaicin
丙硫氧嘧啶
NSC 70461
产品介绍
Propylthiouracil 是一种甲状腺过氧化物酶抑制剂,也是一种5'-脱碘酶抑制剂。

产品描述

Propylthiouracil is a thiourea derivative with an antithyroid property. Propylthiouracil (PTU) interferes with the oxidation of iodine possibly by interaction with peroxidase or a peroxidase-mediated complex reaction, thereby inhibiting synthesis of thyroid hormones tri-iodothyronine (T3) and thyroxine (T4). In addition, this agent inhibits the Type I 5'-deiodinase (D1), an enzyme involved in the peripheral conversion of thyroxine to tri-iodothyronine. This results in decreased plasma triiodothyronine concentrations and decreased entrance of thyroxine into cells thereby reducing thyroid hormone activity.

Cas No.

51-52-5

分子式

C7H10N2OS

分子量

170.23

别名

6-Propyl-2-thiouracil;丙基硫氧嘧啶;6-n-Propylthiouracil;NSC 6498;Pseudocapsaicin;丙硫氧嘧啶;NSC 70461

储存和溶解度

Ethanol:16 mg/mL (94 mM)
DMSO:32 mg/mL (188 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years