N-desmethyl Enzalutamide 是一种 Enzalutamide 的主要活性代谢物，具有与Enzalutamide 相似的一级和二级药效功效，并在与Enzalutamide大致相同的血浆浓度下循环。

N-desmethyl Enzalutamide is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as enzalutamide.

N-desmethyl Enzalutamide is an active metabolite that is thought to contribute to the clinical effects of Enzalutamide Enzalutamide and circulates at approximately the same plasma concentrations as Enzalutamide.?The carboxylic acid metabolite is pharmacologically inactive and circulates at approximately 25 % lower plasma concentrations than Enzalutamide[1].

1242137-16-1

C20H14F4N4O2S

450.41

N-desmethyl MDV 3100;4-[3-[4-氰基-3-(三氟甲基)苯基]-5,5-二甲基-4-氧代-2-硫代-1-咪唑烷基]-2-氟苯甲酰胺

DMSO:48 mg/mL (106.57 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years