Desogestrel 是第三代孕激素类似物,存在于许多口服避孕制剂中。
产品描述
Desogestrel is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
体内活性
Desogestrel is extensively metabolized after oral administration to rats and dogs; In rats, desogestrel is metabolized mainly at the C3, C5, C11, and C15 positions. An hydroxy group is introduced at the 15α-position of desogestrel, followed by conjugation with glucuronic acid. In dogs, desogestrel is mainly metabolized at the C3- and C17-positions[1].
Cas No.
54024-22-5
分子式
C22H30O
分子量
310.481
别名
去氧孕烯;Org-2969;Desogen;Cerazette;Desogestrelum
储存和溶解度
DMSO:58 mg/mL (186.8 mM)
Ethanol:58 mg/mL (186.8 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years