Puromycin 是一种抗生素蛋白质合成抑制剂。它通过与 RNA 结合来抑制蛋白质合成。它还通过 Akt 磷酸化抑制食道癌细胞的生长和转移而用作抗癌药物。它是一种抗肿瘤剂和抗锥虫剂,在研究中用作蛋白质合成的抑制剂。
产品描述
Puromycin is an antibiotic protein synthesis inhibitor. It inhibits protein synthesis by binding to RNA. It also serves as an anticancer drug by suppressing the growth and metastasis in esophagus cancer cells by Akt phosphorylation. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
Cas No.
53-79-2
分子式
C22H29N7O5
分子量
471.52
别名
NSC 3055;Puromycine;NSC3055;NSC-3055
储存和溶解度
DMSO:100mg/mL (143.72mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years