Anhydrotetracycline hydrochloride 是四环素的生物合成前体，是广谱的、有效的竞争性四环素破坏酶抑制剂。它是真核细胞中四环素控制的基因表达系统的效应子。

Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.

Anhydrotetracycline (hydrochloride), a tetracycline biosynthetic precursor, inhibited Tet50, TetX, TetX-3 degradations of tetracyclines with the IC50s of 210 μM, 41 μM and 3 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of demeclocycline with the IC50s of 120 μM, 41 μM, 7 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of chlortetracycline with the IC50s of 210 μM, 75 μM, 26 μM,respectively[1].

13803-65-1

C22H23ClN2O7

462.88

DMSO:125 mg/mL (270.05 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years