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Recilisib
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Recilisib图片
CAS NO:334969-03-8
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
ON 01210
Ex-RAD
RECILISIB 钠盐
产品介绍
Recilisib 是辐射防护剂,能够提高细胞中Akt和PI3K的活性。

产品描述

Recilisib is a radioprotectant,can activate AKT, PI3K activities in cells.

体外活性

Recilisib Sodium increases PI3K activity in HFL-1 cells and murine bone marrow cells in response to radiation exposure. Recilisib Sodium treatment in combination with radiation alters the MAPK signaling pathway.

体内活性

the rate of recovery and differentiation of primitive bone marrow myeloid progenitor cells in mice significantly increased by Recilisib Sodium. Recilisib Sodium in combination with radiation reduces CFU numbers in mice, but the Recilisib Sodium-treated mice consistently retain a capability to form differentiated colonies. Recilisib Sodium treated mice have a progenitor cell population that is never completely depleted by radiation exposure.

Cas No.

334969-03-8

分子式

C16H13ClO4S

分子量

336.79

别名

ON 01210;Ex-RAD;RECILISIB 钠盐

储存和溶解度

DMSO:35.71 mg/mL (106.03 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years