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Gap 26
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Gap 26图片
CAS NO:197250-15-0
包装与价格:
包装价格(元)
1 mg电议
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品介绍
Gap 26 是模拟肽,对应于连接蛋白 43 的残基 63-75,是间隙连接阻断剂。

产品描述

Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.

体外活性

Oscillatory behaviour was abolished by Gap 26 at concentrations of 100-300 microM (IC50 of 20-30 microM), without a change in average tone. No synergy was evident between peptides corresponding to the extracellular loops, and cytoplasmic loop peptides were biologically inactive [1]. Photoliberating InsP(3) in a single cell within a confluent culture triggered an intercellular calcium wave, which was inhibited by the connexin mimetic peptide gap 26 [2].

Cas No.

197250-15-0

分子式

C70H107N19O19S

分子量

1550.8

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years