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Centhaquin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Centhaquin图片
CAS NO:57961-90-7
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Centhaquine (Centhaquin;PMZ-2010) 是一种具有治疗出血性休克的潜力的试剂。Centhaquine (Centhaquin;PMZ-2010) 在出血模型中可以减少全身血管阻力。
Cas No.57961-90-7
别名Centhaquine; PMZ-2010
Canonical SMILESCC1=CC=CC(N(CC2)CCN2CCC3=NC4=C(C=CC=C4)C=C3)=C1
分子式C22H25N3
分子量331.45
溶解度DMSO: 62.5 mg/mL (188.57 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Centhaquine (Centhaquin; PMZ-2010) is a novel agent has the potential for treatment of haemorrhagic shock. Centhaquine (Centhaquin; PMZ-2010) can augment cardiac output, reduce systemic vascular resistance in haemorrhagic models[1][2].

[1]. Srimal RC,et al. Pharmacological studies on 2-(2-(4-(3-methylphenyl)-1-piperazinyl)ethyl) quinoline (centhaquin). I. Hypotensive activity.Pharmacol Res. 1990 May-Jun;22(3):319-29. [2]. Papalexopoulou K, et al. Centhaquin Effects in a Swine Model of Ventricular Fibrillation: Centhaquin and Cardiac Arrest.Heart Lung Circ. 2017 Aug;26(8):856-863.