8-Gingerol分离自姜的根状茎，是口服有效的TRPV1激活剂，EC50值为5.0 μM。8-Gingerol抑制COX-2，还能抑制体外H. pylori的生长。

1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristics. 5. 8-Gingerol seems to be effective in an animal model of rheumatoid arthritis. 6. 8-Gingerol inhibits the anti-serotonin 3 receptor function, exhibits cardiotonic activity. 7. 8-Gingerol affects gastric motility and potentially have an antispasmodic effect on the gastrointestinal system. 8. 8-gingerol inhibited melanogenesis in B16F1 and B16F1 cells by down-regulation of both mitogen-activated protein kinases (MAPK) and protein kinase A (PKA) signaling pathways or through its antioxidant properties.

23513-08-8

C19H30O4

322.445

DMSO:58 mg/mL(179.9 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years