VU591 hydrochloride 是选择性的肾外髓钾通道抑制剂,IC50为 0.24 μM。
产品描述
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentrations up to 10 μM; does not inhibit Kir2.1, Kir2.3 or Kir4.1. Displays similar potency to VU 590
Cas No.
1315380-70-1
分子式
C16H13ClN6O5
分子量
404.77
储存和溶解度
DMSO:16 mg/mL (39.53 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years