λ-Cyhalothrin 是广谱的 II 型合成除虫菊酯杀虫剂，含有 α-氰基，用于防治多种害虫。它是一种钠通道神经毒素，靶向中枢神经系统中神经元膜。

lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. lambda-Cyhalothrin is used to control a wide range of pests in a variety of applications. lambda-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.

The mechanism of λ-Cyhalothrin toxicity produces delay in sodium channel inactivation resulting in persistent depolarization of the nerve membrane. λ-Cyhalothrin produces membrane depolarization, calcium ion infl ux, and neurotransmitter release from rat brain synaptosomes[1]. λ-Cyhalothrin possesses estrogenic properties and is able to function as a xenoestrogen promoting human breast carcinoma cell proliferation in vitro[1].λ-Cyhalothrin has found multiple uses in pest (fleas, cockroaches, flies, and ants) control[1].λ-Cyhalothrin is highly effective against the malaria transmitting species of Anopheles[1].

The effect of λ-Cyhalothrin (i.p.) on memory, movement activity, and co-ordination in mice exposed to bilateral clamping of the carotid arteries (BCCA) is investigated. Neither memory nor movement co-ordination are impaired by BCCA or λ-Cyhalothrin. Exploratory locomotor activity is markedly reduced in the BCCA/LCH group. Spontaneous movement activity is significantly reduced in the BCCA/λ-Cyhalothrin group . Exposure to λ-Cyhalothrin coexisting with BCCA decreases motor activity in the mice in 2 subsequent 30-min[1].

91465-08-6

C23H19ClF3NO3

449.85

Icon;lambda-Cyhalothrin;Karate;λ-氯氟氰菊酯

DMSO:30 mg/mL (66.69mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years