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Phenytoin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Phenytoin图片
CAS NO:57-41-0
包装与价格:
包装价格(元)
500 mg电议
1 g电议
1 mL*10 mM(in DMSO)电议

产品名称
5,5-Diphenylhydantoin
Diphenylhydantoin
苯妥英
产品介绍
Phenytoin是一种有效的电压门控钠离子通道阻滞剂,可减少小鼠乳腺肿瘤的生长和转移,具有抗癫痫活性。

产品描述

Phenytoin is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cortex reducing post-tetanic potentiation at synapses. The reduction of potentiation prevents cortical seizure foci spreading to adjacent areas, stabilizing the threshold against hyperexcitability. In addition, this agent appears to reduce sensitivity of muscle spindles to stretch causing muscle relaxation.

Cas No.

57-41-0

分子式

C15H12N2O2

分子量

252.273

别名

5,5-Diphenylhydantoin;Diphenylhydantoin;苯妥英

储存和溶解度

DMSO:47 mg/mL (186.3 mM)
Ethanol:11 mg/mL (43.6 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years