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Glafenine hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Glafenine hydrochloride图片
CAS NO:65513-72-6
包装与价格:
包装价格(元)
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Glafenin hydrochloride
格拉非宁盐酸盐
产品介绍
Glafenine hydrochloride 是非甾体抗炎药, 可用于研究疼痛的缓解。

产品描述

Glafenine Hydrochloride is an anti-inflammatory agent.

体外活性

Glafenine increases the surface expression of mutant CFTR in baby hamster kidney (BHK) cells to 40% of that observed for wild-type CFTR[2]. Glafenine hydrochloride inhibits the proliferation and clonogenic activity of haSMCs and ECs in a dose-dependent manner. A block in the G2/M phase and a reduction in the G1 phase occurr. The migratory ability of haSMCs is impaired in a dose-dependent manner as well as the extracellular matrix protein tenascin is reduced[3].

细胞实验

Glafenine hydrochloride is added to the culture medium of the smooth muscle cells at three concentrations (10 μM, 50 μM, 100 μM). After 4 days of treatment, cells are harvested and the absolute cell number is counted[3].

Cas No.

65513-72-6

分子式

C19H18Cl2N2O4

分子量

409.26

别名

Glafenin hydrochloride;格拉非宁盐酸盐

储存和溶解度

DMSO:60 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years