DIDS sodium salt 是有效的ABCA1和VDAC1双抑制剂。

DIDS sodium salt is a dual inhibitor of ABCA1 and VDAC1.

DIDS (<400 μM) has no evident cytotoxic effect on cell viability Pre-treatment with DIDS at the concentration of 100 and 200 μM result in a prevented effect on ALA-SDT-induced cell death, while dose at 50 μM has no inhibition effect. Pre-treatment with DIDS (100 μM) clearly inhibit caspase-3 and caspase-9 activation [2].

67483-13-0

C16H10N2Na2O6S4

498.5

MDL101114ZA;4,4'-二异硫氰酸基-2,2'-二苯乙烯磺酸二钠[蛋白质改性试剂]

DMSO:50 mg/mL (100.30 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years